Questions about medication costs?

Turn to LEAP to help understand your out-of-pocket costs

LEAP is ready to help whether you have commercial insurance (for example, from your employer), government-provided coverage (such as Medicare Part D), or if you are uninsured.

Confused about your insurance benefits? LEAP offers educational information on insurance coverage. Learn some basics here.

Understand your insurance benefits

It is important to know that your prescription coverage has two payment parts—what your insurance pays (your drug benefit) and what you pay (your co-pay/coinsurance or out-of-pocket costs). If you need help understanding your insurance benefits for Letairis, please call LEAP.

If you need help paying for your out-of-pocket costs, LEAP may be able to help you find financial support. If you are uninsured or underinsured, there may be programs available to help cover some or all of your treatment costs. For more information contact LEAP at 1-866-664-5327.
Eligible patients pay no more than $5 per month with the Letairis Co-Pay Coupon Program

Patients who have commercial insurance may pay as little as $5 per month for Letairis. Eligible patients are automatically enrolled when they are prescribed branded Letairis.

The Letairis Co-Pay Coupon Program can help with your out-of-pocket costs. If you are eligible, you may pay no more than a $5 co-pay per prescription fill. This program provides co-pay assistance of up to $20,000 per year. Click here for Terms and Conditions.

Call LEAP today at 1-866-664-5327 to see if you are eligible for this program.

Terms and Conditions

The Letairis Co-pay Coupon Program ("Coupon") can be used only by eligible residents of the U.S., Puerto Rico, or U.S. Territories via Certified Pharmacies who dispense Letairis. Product must originate in the U.S. or Puerto Rico, or U.S. Territories. You must be 18 years or older to use the Coupon for yourself or a minor.

The Coupon is not insurance and is not intended to substitute for insurance.

THE COUPON IS VALID ONLY FOR PATIENTS WITH COMMERCIAL INSURANCE AND IS NOT VALID FOR PRESCRIPTIONS THAT ARE ELIGIBLE TO BE REIMBURSED IN WHOLE OR IN PART BY MEDICARE, A MEDICARE PART D PLAN, MEDICAID, TRICARE, VA, DOD, PUERTO RICO GOVERNMENT HEALTH INSURANCE PLAN, OR ANY OTHER FEDERAL OR STATE-FUNDED HEALTHCARE BENEFIT PROGRAM (COLLECTIVELY, "GOVERNMENT PROGRAMS"); OR BY COMMERCIAL PLANS OR OTHER HEALTH OR PHARMACY BENEFIT PROGRAMS THAT REIMBURSE FOR THE ENTIRE COST OF PRESCRIPTION DRUGS.

Medicare Part D Enrollees who are in the prescription drug coverage gap (the "donut hole") are not eligible for the Coupon. Patients who begin receiving prescription benefits from Government Programs at any time will no longer be eligible to use the Coupon. Void where prohibited by law, taxed, or restricted.

Patient, pharmacist, and prescriber agree not to seek reimbursement for all or any part of the benefit received by the patient through the offer. Both patient and pharmacist are each individually responsible for reporting receipts of Coupon benefit to any insurer, health plan, or other third party who pays for, or reimburses, any part of the prescription filled using the Coupon, as required. It is illegal to sell, purchase, trade, or counterfeit, or offer to sell, purchase, trade, or counterfeit the Coupon.

Certain information pertaining to use of the Coupon will be shared with Gilead, the sponsor of the Coupon, and its affiliates. The information disclosed will include the date the prescription is filled, the number of pills or product dispensed by the pharmacist, and the amount of the co-pay that will be paid for by using the Coupon.
For patients with Medicare Part D — know what to expect each month
LEAP can help you better understand your out-of-pocket medication costs through an investigation of your benefits and may be able to help identify resources for financial support.
- LEAP can help you understand how your out-of-pocket costs may vary from month to month, depending on which phase of Medicare Part D coverage you are in
If your Medicare Part D coverage is not enough to cover your Letairis costs, LEAP can assist in identifying an outside source to help cover your out-of-pocket costs, including co-pays, coinsurance, and deductibles. These resources are independent, nonprofit organizations that have their own eligibility criteria and application process.

To better understand your Medicare Part D prescription coverage, visit the Medicare website here.
If you are uninsured or underinsured

If you do not have insurance or your insurance does not cover Letairis costs, LEAP can offer guidance and may be able to help identify financial support for Letairis. LEAP can determine if your financial situation qualifies you to receive your medication free of charge through the Letairis Patient Assistance Program.
LEAP can also offer guidance and may be able to help identify financial support resources outside of your insurance. These third-party resources may be able to help with your out-of-pocket costs, including co-pays, coinsurance, and deductibles. They are independent, nonprofit organizations that have their own eligibility criteria and application process.
If you are struggling to cover your out-of-pocket costs or have no insurance at all, call 1-866-664-5327 today to explore possible support options.

LEAP can also help if you have changes to your insurance

If you encounter changes in your coverage benefits, contact LEAP right away to help you through the transition. LEAP can:

Coordinate the requirements for your new coverage, including Prior Authorization
Help avoid delays in your Letairis shipment

Contact LEAP at 1-866-664-5327.

You can rely on LEAP to help you during these times and to help answer any of the following questions as well:

What if my insurance is changing? How do I make sure Letairis is still available?

LEAP can contact your insurance company to help you find out your new coverage benefits for Letairis.
What if my insurance no longer covers branded Letairis?

If you are running low on Letairis, please contact LEAP. LEAP will assist you in coordinating refills with your Certified Pharmacy.

Contact LEAP to help you with your insurance changes and what to do next. LEAP can also help you find resources to help pay for Letairis.
Now that a generic is available, will my insurance still pay for branded Letairis?

If you and your PAH Specialist decide that branded Letairis is right for you, LEAP can help determine if your insurance plan will cover it. In some cases, you may need to file an appeal. Contact LEAP at 1-866-664-5327 to learn more.
What if my coverage is denied?
- Find out why you were denied insurance coverage
- Determine if you are eligible for third-party support resources or Gilead’s Patient Assistance Program to cover your medication costs
What if I lost my job and I no longer have coverage for Letairis? How can I continue my treatment?
- Assist you in appealing for coverage
- Determine if you are eligible for financial support resources to cover your medication costs

To learn more about how LEAP may help, call 1-866-664-5327

Questions about generics?

Learn more about staying on branded Letairis

Important Safety Information
and Indication

What is the most important information I should know about Letairis?

Letairis can cause serious birth defects if taken during pregnancy.

Females must not be pregnant when they start taking Letairis or become pregnant while taking Letairis
Females who are able to get pregnant must have a negative pregnancy test before starting Letairis, every month while taking Letairis, and 1 month after stopping Letairis. Your doctor will decide when to do the tests, and order the tests for you depending on your menstrual cycle
- Females who are able to get pregnant are females who have entered puberty (even if they have not started their period), and have a uterus, and have not gone through menopause (menopause means that you have not had a period for at least 12 months for natural reasons, or that you have had your ovaries removed)

Females who are able to get pregnant must use two acceptable forms of birth control while taking Letairis and for 1 month after stopping Letairis because the medicine may still be in the body. See the Letairis Medication Guide for acceptable birth control options.

If you have had a tubal sterilization or have an IUD (intrauterine device) or progesterone implant, these methods can be used alone and no other form of birth control is needed
Talk with your doctor to find out about options for acceptable forms of birth control that you may use to prevent pregnancy during treatment with Letairis
If you decide that you want to change the form of birth control, talk with your doctor to be sure that you choose another acceptable form of birth control
Do not have unprotected sex. Talk to your doctor or pharmacist right away if you have unprotected sex or if you think your birth control has failed. Your doctor may tell you to use emergency birth control
Tell your doctor right away if you miss a menstrual period or think you may be pregnant

If you are the parent or caregiver of a female child who started taking Letairis before reaching puberty, you should check your child regularly to see if she is developing signs of puberty. Tell your doctor right away if you notice that she is developing breast buds or any pubic hair. Your child may reach puberty before having her first menstrual period.

Females can only receive Letairis through a restricted program called the Letairis Risk Evaluation and Mitigation (REMS) program. If you are a female who can get pregnant, you must talk to your doctor, understand the benefits and risks of Letairis, and agree to all of the instructions in the Letairis REMS program.

Who should not take Letairis?

Do not take Letairis if:

You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
You have Idiopathic Pulmonary Fibrosis (IPF)

What should I avoid while taking Letairis?

Do not get pregnant. If you miss a menstrual period, or think you might be pregnant, call your doctor right away
Do not breastfeed. It is not known if Letairis passes into your breast milk

What are the other possible side effects of Letairis?

Serious side effects of Letairis can include:

Swelling all over the body (fluid retention) can happen within weeks after starting Letairis. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital
Decreased sperm counts have happened in some men taking a medicine that is like Letairis, which may affect your ability to father a child. Tell your doctor if being able to have children is important to you
Low red blood cell levels (anemia) can happen during the first weeks after starting Letairis. If this happens, you may need a blood transfusion. Your doctor will do blood tests to check your red blood cells before starting Letairis. Your doctor may also do these tests while you are taking Letairis

The most common side effects of Letairis are swelling of hands, legs, ankles and feet (peripheral edema), stuffy nose (nasal congestion), inflamed nasal passages (sinusitis), hot flashes or getting red in the face (flushing). Tell your doctor if you have any side effect that bothers you or does not go away.

The most common side effects of Letairis when taken with tadalafil are swelling of hands, legs, ankles and feet (peripheral edema), headache, stuffy nose (nasal congestion), cough, low red blood cell levels (anemia), indigestion (dyspepsia) or upper respiratory tract infection (bronchitis).

Some medicines that are like Letairis can cause liver problems. Tell your doctor if you get any of these symptoms while taking Letairis: loss of appetite, nausea or vomiting, fever, achiness, generally do not feel well, pain in the upper right stomach (abdominal) area, yellowing of your skin or the whites of your eyes, dark urine, itching.

What should I tell my doctor before taking Letairis?

All your medical conditions. Be sure to tell your doctor if you have a low red blood cell level (anemia) or liver problems
All the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Letairis and other medicines may affect each other, causing side effects. Do not start any new medicines until you check with your doctor
Especially tell your doctor if you take cyclosporine (Gengraf, Neoral, Sandimmune). Your doctor may need to change your dose of Letairis

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Letairis?

Letairis is a prescription medicine used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs.

Letairis can improve your ability to exercise and it can help slow down the worsening of your physical condition and symptoms
When taken with tadalafil, Letairis is used to reduce the risks of your disease progressing and hospitalization due to worsening PAH, and to improve your ability to exercise

Please see full Prescribing Information, including Medication Guide, with important warnings.